Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150334 | 0.73 | CRBN (0.51) | CRBNIKZF3GPBAR1DDB1L3MBTL1 | |
| SCHEMBL20812031 | 0.70 | SMN1; SMN2 (0.54) | CRBNIKZF3DDB1SMN1; SMN2 | |
| SCHEMBL23561213 | 0.70 | CRBN (0.61) | CRBNIKZF3DDB1 | |
| SCHEMBL22307191 | 0.70 | CRBN (0.61) | CRBNIKZF3DDB1 | |
| SCHEMBL20812170 | 0.70 | CRBN (0.47) | CRBNIKZF3DDB1ALDH1A1CHRM2 | |
| SCHEMBL24818238 | 0.68 | CRBN (0.53) | CRBNGPBAR1DDB1TSHR | |
| SCHEMBL20812027 | 0.68 | CRBN (0.51) | CRBNIKZF3DDB1SMN1; SMN2 | |
| SCHEMBL27290606 | 0.67 | CRBN (0.59) | CRBNIKZF3DDB1 | |
| SCHEMBL25873762 | 0.67 | CRBN (0.57) | CRBNIKZF3DDB1ALDH1A1CHRM2 | |
| SCHEMBL2383505 | 0.67 | DDB1 (0.70) | CRBNIKZF3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249048-A1 | ALK PROTEIN REGULATOR AND ANTI-TUMOR APPLICATION THEREOF | 上海科技大学 | 2020-12-17 | — | — | WO | disclosed |