Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043355 | 0.92 | NR1H4 (0.67) | NR1H4 | |
| SCHEMBL22790257 | 0.91 | NR1H4 (0.59) | NR1H4 | |
| SCHEMBL20049125 | 0.89 | NR1H4 (0.66) | NR1H4 | |
| SCHEMBL22789910 | 0.88 | NR1H4 (0.76) | NR1H4 | |
| SCHEMBL29433181 | 0.88 | NR1H4 (0.75) | NR1H4 | |
| SCHEMBL9960281 | 0.85 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL17145696 | 0.85 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL19627422 | 0.85 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL22922693 | 0.85 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL20043335 | 0.85 | NR1H4 (0.65) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008040-B | Compounds for modulating FXR | 南京瑞捷医药科技有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-114008040-A | Compounds for modulating FXR | 南京瑞捷医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |