Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20043352 | 0.92 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL22789987 | 0.88 | NR1H4 (0.68) | NR1H4 | |
| SCHEMBL22790405 | 0.86 | NR1H4 (0.61) | NR1H4 | |
| SCHEMBL20047725 | 0.86 | NR1H4 (0.78) | NR1H4 | |
| SCHEMBL10084823 | 0.86 | NR1H4 (1.00) | NR1H4 | |
| SCHEMBL20043353 | 0.85 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL19122005 | 0.84 | NR1H4 (0.82) | NR1H4 | |
| SCHEMBL20043359 | 0.84 | NR1H4 (0.75) | NR1H4 | |
| SCHEMBL22789958 | 0.84 | NR1H4 (0.65) | NR1H4 | |
| SCHEMBL20049494 | 0.83 | NR1H4 (0.76) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008040-A | Compounds for modulating FXR | 南京瑞捷医药科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |