Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.47 |
| ▸ | FABP1 | P07148 | 5/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22789944 | 0.89 | NR1H4 (0.53) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL22790391 | 0.85 | NR1H4 (0.51) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL22790209 | 0.83 | NR1H4 (0.45) | NR1H4FABP1 | |
| SCHEMBL22790212 | 0.77 | NR1H4 (0.44) | NR1H4 | |
| SCHEMBL22790208 | 0.77 | NR1H4 (0.45) | NR1H4 | |
| SCHEMBL22790342 | 0.77 | POLB (0.57) | NR1H4 | |
| SCHEMBL19690334 | 0.77 | NR1H4 (0.43) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL19628515 | 0.77 | NR1H4 (0.59) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL26965107 | 0.76 | NR1H4 (0.59) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL12168747 | 0.76 | NR1H4 (0.55) | NR1H4FABP1FABP4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |