SCHEMBL2279040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1147395	0.84	EPHX1 (0.44)	MEN1KMT2AMEP1BEPHX1F2
	SCHEMBL2282080	0.82	EPHX1 (0.43)	MEN1KMT2AMEP1BEPHX1MAPK14
	SCHEMBL2286208	0.82	EPHX1 (0.47)	MEN1KMT2AEPHX1F2PRSS1
	SCHEMBL1491605	0.81	MEN1 (0.55)	MEN1KMT2AMMP2MMP9ANPEP
	SCHEMBL1491603	0.81	MEN1 (0.55)	MEN1KMT2AMMP2MMP9ANPEP
	SCHEMBL8203230	0.81	MEN1 (0.50)	MEN1KMT2AMMP2MMP9ANPEP
	SCHEMBL27784577	0.81	MEN1 (0.50)	MEN1KMT2AMMP2MMP9ANPEP
	SCHEMBL2281258	0.80	EPHX1 (0.41)	MMP2MMP9ANPEPLTA4HLAP3
	SCHEMBL2281260	0.80	EPHX1 (0.41)	MMP2MMP9ANPEPLTA4HLAP3
	SCHEMBL2283105	0.78	PSMB5 (0.41)	MEN1KMT2AMEP1BEPHX1PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.