Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.60 |
| ▸ | SLC26A3 | P40879 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787010 | 0.86 | KDM4E (0.50) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL7316459 | 0.82 | P2RY12 (0.61) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL7327157 | 0.82 | P2RY12 (0.63) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL5723325 | 0.81 | P2RY12 (0.62) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL7330143 | 0.80 | P2RY12 (0.61) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL7316417 | 0.78 | P2RY12 (0.59) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL22787011 | 0.78 | KDM4E (0.42) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL8441390 | 0.77 | KDM4E (0.63) | P2RY12SLC26A3KDM4EALDH1A1HPGD | |
| SCHEMBL7330070 | 0.76 | P2RY12 (0.84) | P2RY12 | |
| SCHEMBL7322128 | 0.76 | P2RY12 (0.83) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252398-A1 | PROTEOLYSIS-TARGETING PROTACS INDUCING DEGRADATION OF C-MIC PROTEIN | NORTHWESTERN UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |