Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723325 | 0.84 | P2RY12 (0.62) | P2RY12KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7330143 | 0.83 | P2RY12 (0.61) | P2RY12KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7316459 | 0.83 | P2RY12 (0.61) | P2RY12KDM4EALDH1A1HPGDHTT | |
| SCHEMBL22790797 | 0.82 | P2RY12 (0.60) | P2RY12KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7316417 | 0.81 | P2RY12 (0.59) | P2RY12KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7330070 | 0.79 | P2RY12 (0.84) | P2RY12 | |
| SCHEMBL7322128 | 0.78 | P2RY12 (0.83) | P2RY12 | |
| SCHEMBL7326740 | 0.78 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7326044 | 0.78 | P2RY12 (0.81) | P2RY12 | |
| SCHEMBL7320050 | 0.78 | P2RY12 (0.85) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |