SCHEMBL22790907

SCHEMBL22790907

Cc1nccn1Cc1ccc(C=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
ALDH1A1 P00352 3/20 0.55
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
KCNH2 Q12809 1/20 0.42
BRD4 O60885 1/20 0.41
POLB P06746 1/20 0.41
CYP11B1 P15538 1/20 0.41
HTR1A P08908 1/20 0.41
HTR2C P28335 1/20 0.41
GRM2 Q14416 1/20 0.41
DCTPP1 Q9H773 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31270697 0.86 LMNA (0.74) LMNAL3MBTL1ALDH1A1KMT2ATP53
SCHEMBL3408453 0.84 LMNA (0.59) LMNAL3MBTL1ALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL28317363 0.83 LMNA (0.57) LMNAL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL31729500 0.81 LMNA (0.68) LMNAL3MBTL1ALDH1A1KMT2AKCNH2
SCHEMBL169675 0.81 LMNA (0.68) LMNAL3MBTL1ALDH1A1KMT2ATP53
SCHEMBL301107 0.80 LMNA (0.66) LMNAL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL2950629 0.80 LMNA (0.71) LMNAL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL277927 0.78 LMNA (0.64) LMNAL3MBTL1ALDH1A1KMT2AKCNH2
SCHEMBL11113913 0.78 LMNA (0.64) LMNAL3MBTL1ALDH1A1KMT2AKCNH2
SCHEMBL17102309 0.78 LMNA (0.64) LMNAL3MBTL1ALDH1A1KMT2AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415879-B2 Grafted polymer carrying pendent imidazole functional groups COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-09-16 US disclosed
EP-3983451-B1 GRAFTED POLYMER CARRYING PENDANT IMIDAZOLE FUNCTIONAL GROUPS MICHELIN & CIE (FR) 2023-08-02 EP disclosed
US-20220235164-A1 GRAFTED POLYMER CARRYING PENDENT IMIDAZOLE FUNCTIONAL GROUPS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-07-28 US disclosed
WO-2020249631-A1 GRAFTED POLYMER CARRYING PENDANT IMIDAZOLE FUNCTIONAL GROUPS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-12-17 WO disclosed
WO-2020249623-A1 NOVEL 1,3-DIPOLAR COMPOUNDS COMPRISING AN AROMATIC HETEROCYCLE AND AN IMIDAZOLE RING COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-12-17 WO disclosed