⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017220 | 0.87 | TSHR (0.33) | — | |
| SCHEMBL15601032 | 0.85 | — | — | |
| SCHEMBL12526915 | 0.85 | — | — | |
| SCHEMBL14860422 | 0.85 | CYP2D6 (0.33) | — | |
| SCHEMBL17642692 | 0.85 | — | — | |
| SCHEMBL11008857 | 0.84 | SOS1 (0.31) | — | |
| SCHEMBL443124 | 0.82 | OPRM1 (0.31) | — | |
| SCHEMBL21515959 | 0.82 | TSHR (0.30) | — | |
| SCHEMBL14753708 | 0.82 | SOS1 (0.34) | — | |
| SCHEMBL23606901 | 0.82 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885279-A1 | CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | Janssen Pharmaceutica, N.V. (BE) | 2015-06-24 | — | — | EP | claimed |
| WO-2014028801-A1 | CYCLOPENTYLPYRAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2014-02-20 | — | — | WO | claimed |
| WO-2013177292-A1 | TITANIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2013-11-28 | — | — | WO | claimed |
| WO-2013177284-A1 | HAFNIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2013-11-28 | — | — | WO | claimed |
| WO-2013177269-A2 | ZIRCONIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2013-11-28 | — | — | WO | claimed |
| US-20250381187-A1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC. (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250340565-A1 | CD73 INHIBITOR COMPOUNDS | ADORX THERAPEUTICS LTD (GB) | 2025-11-06 | — | — | US | disclosed |
| US-12440491-B2 | KRAS G12C inhibitors and methods of using the same | AMGEN INC. (US) | 2025-10-14 | — | — | US | disclosed |
| EP-4532495-A1 | CD73 INHIBITOR COMPOUNDS | Adorx therapeutics Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20240359168-A1 | Mesoporous Catalyst Compounds and Uses Thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2024-10-31 | — | — | US | disclosed |
| US-12064752-B2 | Mesoporous catalyst compounds and uses thereof | ExxonMobil Technology and Engineering Company (US) | 2024-08-20 | — | — | US | disclosed |
| EP-1891951-A1 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2008-02-27 | — | — | EP | disclosed |
| US-5300654-A | Dehydrating beta-hydroxyketone in presence of acid catalyst | NIPPON SODA CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0457911-B1 | PREPARATION METHOD FOR ALPHA,BETA-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5214151-A | Method for the preparation of α, β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0457912-A1 | METHOD FOR THE PREPARATION OF $g(a),$g(b)-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0457911-A1 | PREPARATION METHOD FOR ALPHA,BETA-UNSATURATED KETONES. | NIPPON SODA CO (JP) | 1991-11-27 | — | — | EP | disclosed |
| WO-1991007371-A1 | METHOD FOR THE PREPARATION OF α,β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| WO-1991007368-A1 | PREPARATION METHOD FOR α,β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |