Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.51 |
| ▸ | OGA | O60502 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24421697 | 0.86 | HRH3 (0.65) | HRH3OGA | |
| SCHEMBL21933955 | 0.84 | HRH3 (0.48) | HRH3OGA | |
| SCHEMBL2759552 | 0.82 | HRH4 (0.49) | HRH3TLR7 | |
| SCHEMBL9908392 | 0.82 | HRH3 (0.53) | HRH3 | |
| SCHEMBL12217555 | 0.82 | HRH3 (0.49) | HRH3 | |
| SCHEMBL8429477 | 0.80 | CYP1A2 (0.54) | HRH3 | |
| SCHEMBL25608428 | 0.79 | HRH3 (0.47) | HRH3 | |
| SCHEMBL14239245 | 0.79 | MEN1 (0.48) | HRH3OGA | |
| SCHEMBL20443215 | 0.79 | OGA (0.58) | OGATLR8 | |
| SCHEMBL10084688 | 0.79 | HRH3 (0.61) | HRH3OGATLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023233-A1 | EGFR PROTEIN DEGRADANT AND ANTI-TUMOR APPLICATION THEREOF | 上海科技大学 | 2021-02-11 | — | — | WO | disclosed |
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |