Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.45 |
| ▸ | ME1 | P48163 | 1/20 | 0.45 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455986 | 0.89 | HRH3 (0.47) | HRH3 | |
| SCHEMBL22792263 | 0.79 | HRH3 (0.51) | HRH3 | |
| SCHEMBL21421553 | 0.76 | AOC3 (0.37) | HRH3ME2ME1ME3GPR119 | |
| SCHEMBL24421697 | 0.75 | HRH3 (0.65) | HRH3 | |
| SCHEMBL21933955 | 0.73 | HRH3 (0.48) | HRH3AOC3 | |
| SCHEMBL21673748 | 0.73 | AOC3 (0.38) | HRH3ME2ME1ME3GPR119 | |
| SCHEMBL21477154 | 0.72 | DRD3 (0.49) | HRH3ME2ME1ME3 | |
| SCHEMBL19891711 | 0.72 | AOC3 (0.52) | HRH3ME2ME1ME3AOC3 | |
| SCHEMBL9366521 | 0.71 | HRH3 (0.65) | HRH3ME2ME1ME3 | |
| SCHEMBL20230946 | 0.70 | DRD3 (0.52) | ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096987-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |