Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 13/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966947 | 1.00 | NPY5R (0.43) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL22252447 | 0.92 | NPY5R (0.39) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL6553035 | 0.90 | GRM2 (0.40) | NPY5RVNN1GRM2HTR2B | |
| SCHEMBL3074193 | 0.87 | NPY5R (0.37) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL3069122 | 0.87 | NPY5R (0.37) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL3780308 | 0.87 | NPY5R (0.37) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL14081449 | 0.87 | VNN1 (0.40) | NPY5RVNN1CA1CA9GRM2 | |
| SCHEMBL21989900 | 0.80 | VNN1 (0.34) | NPY5RVNN1GRM2HTR2B | |
| SCHEMBL23966948 | 0.75 | NPY5R (0.32) | NPY5R | |
| SCHEMBL22788172 | 0.74 | HTR2B (0.45) | GRM2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249791-A1 | SUBSTITUTED PYRAZOLO[4,3-b]PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |