⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865493 | 1.00 | — | — | |
| SCHEMBL31675230 | 0.74 | LMNA (0.40) | — | |
| SCHEMBL4097383 | 0.74 | — | — | |
| SCHEMBL21118496 | 0.74 | — | — | |
| SCHEMBL20749059 | 0.74 | — | — | |
| SCHEMBL18927381 | 0.72 | — | — | |
| SCHEMBL2525528 | 0.71 | — | — | |
| SCHEMBL16526158 | 0.71 | — | — | |
| SCHEMBL22222387 | 0.71 | — | — | |
| SCHEMBL14948894 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249096-A1 | FUSED RING COMPOUND AS FGFR AND VEGFR DUAL INHIBITOR | 南京明德新药研发有限公司 | 2020-12-17 | — | — | WO | disclosed |