Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22550572 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22550502 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22793106 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL20718178 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22550530 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL22550493 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL22550562 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL20718372 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL20717850 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 | |
| SCHEMBL22550489 | 0.83 | LMNA (0.57) | SMN1; SMN2RAB9ANPC1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251953-A1 | STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-17 | — | — | WO | disclosed |