SCHEMBL2279405

SCHEMBL2279405

ClC1=NCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11064755 0.97
Sulfuric Acid SCHEMBL4689065 0.85 RAD52 (0.41)
SCHEMBL12556606 0.82
Sulfuric Acid SCHEMBL5200708 0.80 RAD52 (0.35)
SCHEMBL1586471 0.78
SCHEMBL3742115 0.67 NISCH (0.56)
SCHEMBL1001560 0.63
SCHEMBL12003931 0.63
SCHEMBL16730 0.62
SCHEMBL3957418 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119859216-A Polar functionalized conjugated diene polymer and preparation method thereof 东华大学 2025-04-22 CN claimed
CN-119462482-A Chiral quaternary nitrogen guanidine salt derived from amino acid, preparation method and application thereof 四川大学 2025-02-18 CN claimed
CN-117384612-A Temperature-resistant corrosion inhibitor and preparation method thereof 碳中能源科技(北京)有限公司 2024-01-12 CN claimed
CN-113185461-A Synthesis method for kilogram-level enlargeable scale production of chiral biguanide catalyst 中新国际联合研究院 2021-07-30 CN claimed
CN-113185500-A Industrial synthesis method of modified chiral biguanide phase transfer catalyst 中新国际联合研究院 2021-07-30 CN claimed
CN-110627809-A Polysubstituted thieno [2,3-b ] pyridine derivative and preparation method and application thereof 北京大学 2019-12-31 CN claimed
CN-108712912-A The immune response enhanced in water biological species 拜耳动物保健有限责任公司 2018-10-26 CN claimed
CN-108472255-A Methods of modulating cytoplasmic DNA monitoring molecules 拜耳动物保健有限责任公司 2018-08-31 CN claimed
CN-108239141-A A kind of preparation method of anamorelin 江苏先声药业有限公司 2018-07-03 CN claimed
CN-100527956-C Composition for use as an adjuvant, and method of preparing the composition CALTEX AUSTRALIA PETROLEUM PTY (AU) 2009-08-19 CN claimed
US-7279498-B2 Substituted aryl amides as IP antagonists ROCHE PALO ALTO LLC (US) 2007-10-09 US claimed
CN-1870890-A Composition for use as an adjuvant and process for its preparation CALTEX AUSTRALIA PETROLEUM PTY (AU) 2006-11-29 CN claimed
US-6998414-B2 Substituted arylamides as IP antagonists ROCHE PALO ALTO LLC (US) 2006-02-14 US claimed
EP-1622611-A1 IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2006-02-08 EP claimed
US-20060004075-A1 Substituted aryl amides as IP antagonists ROCHE PALO ALTO LLC 2006-01-05 US claimed
WO-2004096213-A1 IMIDAZOLIN-2-YLAMINOPHENYL AMIDES AS IP ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2004-11-11 WO claimed
US-20040220247-A1 Substituted arylamides as IP antagonists ROCHE PALO ALTO LLC 2004-11-04 US claimed
EP-0887346-A2 Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives, their preparation and their use as alpha1A/1L adrenoceptor agonists F. HOFFMANN-LA ROCHE AG (CH) 1998-12-30 EP claimed
CN-114630661-B Functionally modified maytansinoids and compositions and methods of use thereof 佐治亚大学研究基金会股份有限公司 2025-06-24 CN disclosed
US-4125620-A HYPOTENSIVE BOEHRINGER INGELHEIM GMBH (DE) 1978-11-14 US disclosed