Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.55 |
| ▸ | GBA1 | P04062 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701235 | 1.00 | CYP19A1 (0.65) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL25836828 | 1.00 | CYP19A1 (0.65) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL3546675 | 1.00 | CYP19A1 (0.65) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL25837226 | 1.00 | CYP19A1 (0.65) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL3549774 | 0.98 | CYP19A1 (0.62) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL5021080 | 0.92 | L3MBTL1 (0.56) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL14982736 | 0.88 | CYP19A1 (0.50) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL24675720 | 0.87 | HRH4 (0.66) | CYP19A1HRH4HRH3GBA1EPHX2 | |
| SCHEMBL21318217 | 0.87 | HRH4 (0.66) | CYP19A1HRH4HRH3GBA1EPHX2 | |
| SCHEMBL9926292 | 0.87 | CYP19A1 (0.63) | CYP19A1HRH4HRH3GBA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |