Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25108868 | 1.00 | ALDH1A1 (0.42) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25109337 | 0.95 | EPHX2 (0.48) | ALDH1A1EPHX2LMNAKMT2ADEGS1 | |
| SCHEMBL25468398 | 0.91 | EPHX2 (0.48) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25468400 | 0.91 | EPHX2 (0.48) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25110465 | 0.91 | EPHX2 (0.48) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25110997 | 0.91 | EPHX2 (0.48) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25109404 | 0.87 | EPHX2 (0.45) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL24514526 | 0.87 | KMT2A (0.45) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL25110485 | 0.87 | TSHR (0.49) | ALDH1A1EPHX2LMNAKMT2AMEN1 | |
| SCHEMBL22794639 | 0.87 | EPHX2 (0.43) | ALDH1A1EPHX2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |