Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 3/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22796193 | 0.85 | PPARG (0.42) | PPARGPPARDPPARAIAPPCCR5 | |
| Alnuside B SCHEMBL22796510 | 0.80 | PPARG (0.49) | PPARGPPARDPPARAIAPPPOLB | |
| Alnuside B SCHEMBL12672476 | 0.80 | PPARG (0.49) | PPARGPPARDPPARAIAPPPOLB | |
| SCHEMBL14790109 | 0.78 | IAPP (0.52) | IAPPPOLBGAALMNAKDM4E | |
| Oregonin SCHEMBL29389089 | 0.76 | PPARG (0.46) | PPARGPPARDPPARAIAPPCCR5 | |
| Oregonin SCHEMBL12659728 | 0.76 | PPARG (0.46) | PPARGPPARDPPARAIAPPCCR5 | |
| SCHEMBL14790110 | 0.73 | IAPP (0.57) | IAPPPOLBGAACYP3A4ADRB2 | |
| SCHEMBL29388330 | 0.73 | IAPP (0.57) | IAPPPOLBGAACYP3A4ADRB2 | |
| SCHEMBL12556406 | 0.72 | IAPP (0.56) | IAPPCCR5POLBGAALMNA | |
| SCHEMBL21203290 | 0.71 | IAPP (0.72) | IAPPCCR5POLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392223-A1 | IL-17A ACTIVITY INHIBITOR AND USE THEREOF | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392223-A1 | IL-17A ACTIVITY INHIBITOR AND USE THEREOF | IL17A, IL23R, IL15RA | PPARG 1058/4885PPARD 2704/4885PPARA 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.