Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388330 | 1.00 | IAPP (0.57) | IAPPPOLBGAACYP3A4CYP2C8 | |
| SCHEMBL14790109 | 0.95 | IAPP (0.52) | IAPPPOLBGAACYP3A4CYP2C8 | |
| SCHEMBL14790111 | 0.85 | POLB (0.47) | IAPPPOLBGAACYP3A4CYP2C8 | |
| SCHEMBL6378341 | 0.83 | GAA (0.78) | POLBGAACYP3A4CYP2C8CYP2C9 | |
| SCHEMBL13250105 | 0.81 | IAPP (0.49) | IAPPPOLBGAACYP3A4CYP2C8 | |
| SCHEMBL12259973 | 0.81 | IAPP (0.62) | IAPPPOLBGAACYP3A4CYP2C8 | |
| SCHEMBL12556404 | 0.81 | IAPP (0.62) | IAPPPOLBGAACYP3A4CYP2C8 | |
| Hirsutanonol SCHEMBL1894697 | 0.80 | POLB (0.63) | IAPPPOLBGAACYP3A4CYP2C8 | |
| Hirsutanonol SCHEMBL13250104 | 0.80 | POLB (0.63) | IAPPPOLBGAACYP3A4CYP2C8 | |
| Hirsutanonol SCHEMBL1816532 | 0.80 | POLB (0.63) | IAPPPOLBGAACYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072450-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYLHEPTANOIDS FROM ALNUS JAPONICA | RNL BIO CO., LTD. (KR) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072450-A1 | ANTIOXIDATIVE AND HEPATOPROTECTIVE COMPOSITIONS CONTAINING DIARYLHEPTANOIDS FROM ALNUS JAPONICA | NR1H2, ALOX15B, ALOX12 | IAPP 821/4885POLB 1297/4885GAA 2091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.