SCHEMBL22798002

SCHEMBL22798002

CCN(Cc1cnco1)C1CCN(OC(=O)C(F)(F)F)CC1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22797950 0.89 GPR119 (0.36) GPR119
SCHEMBL22797926 0.88 GPR119 (0.36) GPR119
Trifluoroacetic Acid SCHEMBL22798001 0.78 SLC6A2 (0.47)
SCHEMBL18469975 0.78 KDM4E (0.39) GPR119
SCHEMBL22797981 0.71 CHRM4 (0.38) GPR119
SCHEMBL20596707 0.70 DRD3 (0.31)
SCHEMBL20596704 0.69 DRD3 (0.32)
SCHEMBL22813548 0.69 DRD3 (0.39) GPR119
SCHEMBL18429015 0.69 CHRM4 (0.46) GPR119
SCHEMBL18469971 0.68 KDM4E (0.37) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822262-B1 MUSCARINIC AGONISTS HEPTARES THERAPEUTICS LTD (GB) 2024-03-27 EP disclosed
EP-3822262-A1 MUSCARINIC AGONISTS Heptares Therapeutics Limited (GB) 2021-05-19 EP disclosed
EP-3331869-B1 MUSCARINIC AGONISTS HEPTARES THERAPEUTICS LTD (GB) 2020-12-23 EP disclosed