Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811291 | 1.00 | ELANE (0.53) | ELANECTSGCMA1PREPACE | |
| SCHEMBL18620885 | 1.00 | ELANE (0.53) | ELANECTSGCMA1PREPACE | |
| SCHEMBL22209446 | 0.91 | ELANE (0.53) | ELANECTSGCMA1PREP | |
| SCHEMBL18620672 | 0.91 | ELANE (0.53) | ELANECTSGCMA1PREP | |
| SCHEMBL22798165 | 0.89 | CMA1 (0.51) | ELANECTSGCMA1ACE | |
| SCHEMBL22209387 | 0.89 | CMA1 (0.51) | ELANECTSGCMA1ACE | |
| SCHEMBL3471466 | 0.88 | LMNA (0.53) | ELANECTSGPREPACE | |
| SCHEMBL20484733 | 0.88 | LMNA (0.53) | ELANECTSGPREPACE | |
| SCHEMBL18586542 | 0.88 | ELANE (0.55) | ELANECTSGCMA1PREPACE | |
| SCHEMBL22798449 | 0.88 | ELANE (0.55) | ELANECTSGCMA1PREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |