Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.59 |
| ▸ | KDR | P35968 | 9/20 | 0.48 |
| ▸ | BRAF | P15056 | 8/20 | 0.48 |
| ▸ | GSK3B | P49841 | 8/20 | 0.47 |
| ▸ | GSK3A | P49840 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797762 | 0.93 | SCN9A (0.67) | SCN9AGSK3BMAPT | |
| SCHEMBL20595167 | 0.93 | GSK3B (0.52) | SCN9AKDRBRAFGSK3BGSK3A | |
| SCHEMBL22797805 | 0.86 | GSK3B (0.52) | SCN9AKDRBRAFGSK3BGSK3A | |
| SCHEMBL30450902 | 0.85 | SCN9A (0.68) | SCN9AGSK3BMAPT | |
| SCHEMBL22798252 | 0.85 | SCN9A (0.68) | SCN9AGSK3BMAPT | |
| SCHEMBL22797811 | 0.85 | GSK3B (0.52) | SCN9AKDRBRAFGSK3BGSK3A | |
| SCHEMBL20595171 | 0.84 | SCN9A (0.56) | SCN9AKDRBRAFGSK3BGSK3A | |
| SCHEMBL20595154 | 0.84 | SCN9A (0.76) | SCN9AGSK3BMAPT | |
| SCHEMBL20595189 | 0.84 | SCN9A (0.66) | SCN9AGSK3BMAPT | |
| SCHEMBL30450528 | 0.84 | SCN9A (0.66) | SCN9AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | claimed |