Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595189 | 1.00 | SCN9A (0.66) | SCN9AMAPTGSK3BGPR52KMT2A | |
| SCHEMBL22798252 | 0.91 | SCN9A (0.68) | SCN9AMAPTGSK3BGPR52KMT2A | |
| SCHEMBL30450902 | 0.91 | SCN9A (0.68) | SCN9AMAPTGSK3BGPR52KMT2A | |
| SCHEMBL22797762 | 0.90 | SCN9A (0.67) | SCN9AMAPTGSK3BGPR52KMT2A | |
| SCHEMBL22798231 | 0.90 | SCN9A (0.52) | SCN9AMAPTGPR52KMT2AMCHR1 | |
| SCHEMBL20595154 | 0.89 | SCN9A (0.76) | SCN9AMAPTGSK3BMRGPRX4 | |
| SCHEMBL20595159 | 0.88 | SCN9A (0.51) | SCN9AMAPTGPR52KMT2AMCHR1 | |
| SCHEMBL22809634 | 0.88 | GPR52 (0.51) | SCN9AMAPTGPR52KMT2AMRGPRX4 | |
| SCHEMBL20595207 | 0.88 | SCN9A (0.65) | SCN9AMAPTKMT2AMCHR1MRGPRX4 | |
| SCHEMBL30450908 | 0.88 | SCN9A (0.65) | SCN9AMAPTKMT2AMCHR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |