Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184074 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL21856128 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL21631570 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL30833163 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL21952182 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL22799205 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL22835894 | 0.74 | PPM1D (0.36) | PPM1D | |
| SCHEMBL3568839 | 0.74 | PPM1D (0.37) | PPM1D | |
| SCHEMBL20571950 | 0.73 | PPM1D (0.32) | PPM1D | |
| SCHEMBL18319545 | 0.73 | PPM1D (0.32) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753941-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Blueray Biopharma Co., Ltd. (CN) | 2020-12-23 | — | — | EP | disclosed |