SCHEMBL22799301

SCHEMBL22799301

c1ccc(-c2ccccc2-c2ccc(Nc3cccc4c3C3(c5ccccc5-4)C4CC5CC(C4)CC3C5)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SIGMAR1 Q99720 1/20 0.34
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
AKR1C3 P42330 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
RECQL P46063 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22797649 0.96 MEN1 (0.34) MEN1KMT2ANPSR1SIGMAR1MAPK13
SCHEMBL23571922 0.91 MEN1 (0.38) MEN1KMT2ANPSR1SIGMAR1MAPK14
SCHEMBL22799278 0.91 MEN1 (0.35) MEN1KMT2ANPSR1SIGMAR1AKR1C3
SCHEMBL22797619 0.90 MEN1 (0.33) MEN1KMT2ANPSR1
SCHEMBL22797589 0.89 MEN1 (0.40) MEN1KMT2ANPSR1SIGMAR1
SCHEMBL22797214 0.89 MEN1 (0.41) MEN1KMT2ANPSR1SIGMAR1
SCHEMBL22797600 0.88 SIRT2 (0.39) MEN1KMT2ANPSR1SIGMAR1AKR1C3
SCHEMBL24728358 0.87 SIRT2 (0.40) MEN1KMT2ANPSR1SIGMAR1AKR1C3
SCHEMBL22797226 0.87 SIGMAR1 (0.36) MEN1KMT2ANPSR1SIGMAR1MAPK13
SCHEMBL24728435 0.86 MAPT (0.39) MEN1KMT2AKDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed