Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22799768 | 1.00 | CYP4F2 (0.39) | CYP4F2CYP4A11MAPTSLC16A3THRB | |
| SCHEMBL22800230 | 1.00 | CYP4F2 (0.39) | CYP4F2CYP4A11MAPTSLC16A3THRB | |
| SCHEMBL22800083 | 0.84 | MAPT (0.38) | MAPTHPGDHTTKMT2AHSD17B10 | |
| SCHEMBL22799765 | 0.82 | MAPT (0.35) | MAPTSLC16A3THRBTHRAALDH1A1 | |
| SCHEMBL22801013 | 0.74 | MAPT (0.40) | MAPTTHRBTHRATSHRHTT | |
| SCHEMBL12984319 | 0.73 | TSHR (0.41) | CYP4F2CYP4A11THRBL3MBTL1ALDH1A1 | |
| SCHEMBL22800186 | 0.72 | ICMT (0.37) | MAPTALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL22800999 | 0.72 | CAPN1 (0.47) | MAPTTHRBTHRATSHRHTT | |
| SCHEMBL13582980 | 0.72 | S1PR2 (0.38) | CYP4F2CYP4A11THRBL3MBTL1ALDH1A1 | |
| SCHEMBL12984118 | 0.71 | TSHR (0.44) | CYP4F2CYP4A11THRBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | Knobbe, Martens, Olson & Bear, LLP | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN2, CAPN1 | CYP4F2 4771/4885CYP4A11 4541/4885MAPT 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.