SCHEMBL2280206

SCHEMBL2280206

C=CCOC(=O)C(CCCCCCCCCCCC)(CC(=O)O)S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 3/20 0.32
FFAR1 O14842 2/20 0.32
CPT2 P23786 1/20 0.32
PAM P19021 2/20 0.31
EPHX2 P34913 2/20 0.31
HSD17B10 Q99714 2/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4006588 1.00 TSHR (0.44) TSHRZDHHC20ZDHHC2MEN1KMT2A
SCHEMBL10707458 0.88 TSHR (0.43) TSHRZDHHC20ZDHHC2MEN1KMT2A
Potassium Ion SCHEMBL10748165 0.88 TSHR (0.43) TSHRZDHHC20ZDHHC2MEN1KMT2A
SCHEMBL1925048 0.88 TSHR (0.43) TSHRZDHHC20ZDHHC2MEN1KMT2A
SCHEMBL15265820 0.86 TSHR (0.40) TSHR
SCHEMBL9979036 0.85 MEN1 (0.46) TSHRMEN1KMT2AMAPTATM
SCHEMBL1462300 0.85 TSHR (0.38) TSHRZDHHC20ZDHHC2MEN1KMT2A
SCHEMBL28165393 0.84 TSHR (0.40) TSHRZDHHC20ZDHHC2
SCHEMBL7778396 0.84 NAAA (0.40) TSHREPHX2
SCHEMBL9437676 0.84 NAAA (0.40) TSHREPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219916-A Waterbased methylol (meth)acrylamide acrylic polymer and an acrylic hydrosol coating composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US claimed
CN-106189469-B Aqueous coating composition having low or zero VOC and comprising encapsulated or polymer adsorbed pigment and reduced binder 罗门哈斯公司 2020-10-30 CN disclosed
US-8637609-B1 Blends of acrylic latices and polyurethane dispersions for coatings THE SHERWIN-WILLIAMS COMPANY (US) 2014-01-28 US disclosed
US-8273684-B2 Seed coating composition E I DU PONT DE NEMOURS AND COMPANY (US) 2012-09-25 US disclosed
US-20110245078-A1 SEED COATING COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-06 US disclosed
US-7989391-B2 Aqueous carrier, pigment and acrylic latex binder with comonomers of methyl methacrylate, styrene, 2-ethylhexyl acrylate, methylol methacrylamide, hydroxyethyl acrylate and 1- methacrylic acid and/or a graft copolymer dispersant neutralized with base or amine; color strength; dustless E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-02 US disclosed
US-20080103044-A1 Seed coating composition E. I. DU PONT DE NEMOURS AND COMPANY 2008-05-01 US disclosed
EP-0897399-B1 ACRYLIC POLYMER COMPOUNDS DU PONT (US) 2002-01-02 EP disclosed
EP-0845973-A4 NAIL ENAMEL COMPOSITIONS REVLON CONSUMER PROD CORP (US) 1999-05-06 EP disclosed
EP-0897399-A1 ACRYLIC POLYMER COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-24 EP disclosed
EP-0421609-B1 Waterbased acrylic coating composition DU PONT (US) 1993-11-18 EP disclosed
US-5221584-A Automotive quality clear coat and/or pigmented color coat E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-22 US disclosed
US-5219916-A Waterbased methylol (meth)acrylamide acrylic polymer and an acrylic hydrosol coating composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US disclosed
US-5204404-A Automobile paints E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-20 US disclosed
WO-1992022612-A1 WATERBORNE ACRYLOURETHANE PIGMENT DISPERSANT POLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-23 WO disclosed
US-5166254-A Protective coatings for automobiles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-24 US disclosed
US-5051464-A Acrylated polyurethane with a chain extender as a paint for automobiles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-24 US disclosed
EP-0421609-A2 Waterbased acrylic coating composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-10 EP disclosed
US-5006413-A Waterbased methylol (meth)acrylamide acrylic polymer and polyurethane containing coating composition E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-04-09 US disclosed
US-4954559-A AUTOMOBILE COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-04 US disclosed