SCHEMBL22802256

SCHEMBL22802256

c1ccc(-c2ncnc(-c3ccc4oc5ccccc5c4c3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.46
▸ HPGD P15428 5/20 0.46
▸ NPC1 O15118 4/20 0.46
▸ SMN1; SMN2 Q16637 4/20 0.46
▸ ALDH1A1 P00352 4/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ CHEK2 O96017 1/20 0.43
▸ PLA2G2A P14555 3/20 0.43
▸ PLA2G4A P47712 3/20 0.43
▸ LMNA P02545 2/20 0.42
▸ AHR P35869 2/20 0.42
▸ PLA2G10 O15496 1/20 0.41
▸ GABRP O00591 1/20 0.39
▸ GABRD O14764 1/20 0.39
▸ CA12 O43570 1/20 0.39
▸ TNKS O95271 1/20 0.39
▸ CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30960269 1.00 MAPT (0.46) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL22377057 0.98 PLA2G2A (0.46) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL30973822 0.95 PLA2G2A (0.48) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL16441416 0.95 MAPT (0.50) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL15835959 0.93 MAPT (0.49) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL22376020 0.92 PLA2G2A (0.43) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL29761259 0.92 AHR (0.45) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL18215027 0.92 AHR (0.45) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL23268362 0.92 HPGD (0.50) MAPTHPGDNPC1SMN1; SMN2ALDH1A1
SCHEMBL17214814 0.92 HPGD (0.50) MAPTHPGDNPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 — — EP disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 — — US disclosed
US-20230225203-A1 ORGANIC LUMINESCENT ELEMENT KYULUX, INC. (JP) 2023-07-13 — — US disclosed
US-11569455-B2 Compound for organic optoelectronic device, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2023-01-31 — — US disclosed
US-20200395551-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-12-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744151-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND MAPT 567/4885HPGD 832/4885NPC1 2142/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 MAPT 966/4885HPGD 474/4885NPC1 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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