Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 15/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775596 | 1.00 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550393 | 1.00 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775424 | 1.00 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550414 | 1.00 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775254 | 0.94 | GRIN2B (0.73) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550298 | 0.94 | GRIN2B (0.73) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL25499112 | 0.94 | GRIN2B (0.73) | GRIN2BGRIN1CYP2C9KCNH2 | |
| Trifluoroacetic Acid SCHEMBL29550904 | 0.92 | GRIN2B (0.70) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550454 | 0.89 | GRIN2B (0.62) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775223 | 0.89 | GRIN2B (0.62) | GRIN2BGRIN1CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249792-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |