Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.73 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775254 | 1.00 | GRIN2B (0.73) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550298 | 1.00 | GRIN2B (0.73) | GRIN2BGRIN1CYP2C9KCNH2 | |
| Trifluoroacetic Acid SCHEMBL29550904 | 0.97 | GRIN2B (0.70) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550393 | 0.94 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22802331 | 0.94 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775424 | 0.94 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22775596 | 0.94 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL29550414 | 0.94 | GRIN2B (0.66) | GRIN2BGRIN1CYP2C9KCNH2 | |
| SCHEMBL22802733 | 0.93 | GRIN2B (0.63) | GRIN2BGRIN1 | |
| SCHEMBL29550456 | 0.93 | GRIN2B (0.63) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151006-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151006-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR | GRIN2B, GRIN2A, GRIN3A | GRIN2B 1/4885GRIN1 5/4885CYP2C9 2559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.