Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29911066 | 0.83 | TRPC6 (0.62) | TRPC6 | |
| SCHEMBL21284348 | 0.83 | TRPC6 (0.62) | TRPC6 | |
| SCHEMBL29911271 | 0.82 | TRPC6 (0.61) | TRPC6 | |
| SCHEMBL29911158 | 0.82 | TRPC6 (0.64) | TRPC6 | |
| SCHEMBL29911330 | 0.82 | TRPC6 (0.61) | TRPC6 | |
| SCHEMBL21284441 | 0.82 | TRPC6 (0.61) | TRPC6 | |
| SCHEMBL21284347 | 0.82 | TRPC6 (0.64) | TRPC6 | |
| SCHEMBL21284434 | 0.82 | TRPC6 (0.61) | TRPC6 | |
| SCHEMBL21274233 | 0.81 | TRPC6 (0.59) | TRPC6 | |
| SCHEMBL30803595 | 0.81 | TRPC6 (0.59) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752499-B1 | INHIBITORS OF TRPC6 | BOEHRINGER INGELHEIM INT (DE) | 2024-03-27 | — | — | EP | disclosed |
| CN-111770918-B | Inhibitors of TRPC6 | 勃林格殷格翰国际公司 | 2024-02-27 | — | — | CN | disclosed |
| US-11485740-B2 | Inhibitors of TRPC6 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-11-01 | — | — | US | disclosed |
| US-20200399282-A1 | INHIBITORS OF TRPC6 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399282-A1 | INHIBITORS OF TRPC6 | TRPC6, TRPC1, TRPC4 | TRPC6 1/4885 |
| US-11485740-B2 | Inhibitors of TRPC6 | TRPC6, TRPC1, TRPC4 | TRPC6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.