Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048226 | 0.85 | MEN1 (0.54) | GRM2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL11027295 | 0.82 | GRM2 (0.50) | GRM2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL11112986 | 0.81 | HSD17B10 (0.56) | GRM2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL11601732 | 0.80 | HSD17B10 (0.55) | GRM2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL11654170 | 0.74 | GRM2 (0.44) | GRM2LMNAADRB3GPR183 | |
| SCHEMBL4946805 | 0.74 | GRM2 (0.64) | GRM2ADRB3GPR183 | |
| SCHEMBL4945422 | 0.72 | GRM2 (0.43) | GRM2ADRB3GPR183 | |
| SCHEMBL11659608 | 0.71 | GRM2 (0.41) | GRM2ADRB3GPR183 | |
| SCHEMBL11707480 | 0.70 | ALDH1A1 (0.47) | GRM2MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL11707753 | 0.70 | GRM2 (0.43) | GRM2MEN1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252041-A1 | SWELL1-LRRC8 COMPLEX MODULATORS | WASHINGTON UNIVERSITY (US) | 2020-12-17 | — | — | WO | disclosed |