Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30433854 | 0.77 | MIF (0.43) | MEN1KMT2AMETAP2HTTALDH1A1 | |
| SCHEMBL22824613 | 0.77 | MIF (0.43) | MEN1KMT2AMETAP2HTTALDH1A1 | |
| SCHEMBL30528336 | 0.77 | CCR1 (0.61) | MEN1KMT2AMETAP2HTTRECQL | |
| SCHEMBL13750594 | 0.74 | CYP1A2 (0.40) | METAP2HTTRECQLALDH1A1CYP1A2 | |
| SCHEMBL7509409 | 0.72 | CCR1 (0.58) | KMT2AMETAP2CYP1A2 | |
| SCHEMBL22127684 | 0.70 | METAP2 (0.33) | METAP2 | |
| SCHEMBL5788862 | 0.70 | HTT (0.42) | METAP2HTTRECQLALDH1A1CYP1A2 | |
| SCHEMBL78566 | 0.69 | NISCH (0.50) | METAP2HTTRECQLALDH1A1CYP1A2 | |
| SCHEMBL29598957 | 0.69 | NISCH (0.50) | METAP2HTTRECQLALDH1A1CYP1A2 | |
| SCHEMBL29454745 | 0.69 | NISCH (0.50) | METAP2HTTRECQLALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272417-B | 2-methyl-1, 8-naphthyridine compound and preparation method and application thereof | 五邑大学 | 2021-07-13 | — | — | CN | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |