Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055423 | 0.77 | MAP4K4 (0.39) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL22821915 | 0.77 | SMPD3 (0.41) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL22595104 | 0.77 | EGFR (0.36) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL398829 | 0.72 | MAP4K4 (0.60) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL22821756 | 0.70 | SMPD3 (0.34) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL19942301 | 0.68 | MAP4K4 (0.46) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL2314012 | 0.67 | NUDT1 (0.52) | SMPD3AKT1DYRK1A | |
| SCHEMBL23338649 | 0.65 | MAP4K4 (0.47) | MAP4K4ALDH1A1KDM4ECYP2C19PDE10A | |
| SCHEMBL258973 | 0.64 | HTT (0.39) | MAP4K4SMPD3ALDH1A1GLAKDM4E | |
| SCHEMBL17505371 | 0.63 | MAP4K4 (0.36) | MAP4K4SMPD3ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253862-A1 | NITROGEN-CONTAINING ARYL PHOSPHORUS OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-24 | — | — | WO | disclosed |