⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858779 | 0.73 | — | — | |
| SCHEMBL27503722 | 0.71 | CA1 (0.35) | — | |
| SCHEMBL27990528 | 0.69 | CA1 (0.33) | — | |
| SCHEMBL29102523 | 0.68 | — | — | |
| SCHEMBL27841199 | 0.67 | — | — | |
| SCHEMBL15081209 | 0.66 | AOC1 (0.32) | — | |
| SCHEMBL27451643 | 0.66 | — | — | |
| SCHEMBL9317681 | 0.64 | — | — | |
| SCHEMBL8333876 | 0.64 | — | — | |
| SCHEMBL6187063 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983384-A1 | N-(PHENYL)-INDOLE-3-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS GPR17 MODULATORS FOR TREATING CNS DISORDERS SUCH AS MULTIPLE SCLEROSIS | UCB Pharma GmbH (DE) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020254289-A1 | N-(PHENYL)-INDOLE-3-SULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS GPR17 MODULATORS FOR TREATING CNS DISORDERS SUCH AS MULTIPLE SCLEROSIS | UCB PHARMA GMBH (DE) | 2020-12-24 | — | — | WO | disclosed |