Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22805037 | 0.88 | PLOD2 (0.69) | NR4A2MAOBNPC1RAB9APLOD2 | |
| SCHEMBL22804725 | 0.86 | MAOB (0.61) | NR4A2MAOBNPC1RAB9APLOD2 | |
| SCHEMBL1115991 | 0.86 | NR4A1 (0.60) | NR4A2MAOBNPC1RAB9APLOD2 | |
| SCHEMBL22804566 | 0.86 | S1PR1 (0.48) | NR4A2MAOBMAOAPLOD2 | |
| SCHEMBL29623539 | 0.86 | S1PR1 (0.48) | NR4A2MAOBMAOAPLOD2 | |
| SCHEMBL22804709 | 0.84 | PLOD2 (0.58) | PLOD2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL584065 | 0.84 | PLOD2 (0.70) | NPC1RAB9APLOD2MAPTALDH1A1 | |
| SCHEMBL22804448 | 0.83 | PLOD2 (0.48) | NR4A2MAOBNPC1RAB9APLOD2 | |
| SCHEMBL22804502 | 0.82 | MAOB (0.63) | MAOBMAOARAB9AMAPTALDH1A1 | |
| SCHEMBL22804447 | 0.80 | PLOD2 (0.50) | NR4A2MAOBMAOAPLOD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986875-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | Bayer Aktiengesellschaft (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020254490-A1 | PHENOXYPHENYL HYDROXYISOXAZOLINES AND ANALOGUES AS NEW ANTIFUNGAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-24 | — | — | WO | disclosed |