⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626857 | 0.63 | — | — | |
| SCHEMBL28509889 | 0.62 | — | — | |
| SCHEMBL16332378 | 0.61 | — | — | |
| SCHEMBL16701997 | 0.59 | TDP1 (0.34) | — | |
| SCHEMBL14971313 | 0.56 | — | — | |
| SCHEMBL4808079 | 0.55 | ALDH1A1 (0.32) | — | |
| Methoxymethane SCHEMBL27637909 | 0.52 | HSD17B10 (0.67) | — | |
| SCHEMBL10778338 | 0.52 | ALDH1A1 (0.62) | — | |
| SCHEMBL19086367 | 0.52 | — | — | |
| SCHEMBL2105879 | 0.51 | ALDH1A1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479820-B2 | Pyridin-3-yl derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-11-25 | — | — | US | disclosed |
| CN-114026082-B | Pyridin-3-yl derivatives | 爱杜西亚药品有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-20220251068-A1 | PYRIDIN-3-YL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-08-11 | — | — | US | disclosed |
| EP-3986884-A1 | PYRIDIN-3-YL DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-04-27 | — | — | EP | disclosed |
| CN-114026082-A | Pyridin-3-yl derivatives | 爱杜西亚药品有限公司 | 2022-02-08 | — | — | CN | disclosed |
| WO-2020254408-A1 | PYRIDIN-3-YL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-24 | — | — | WO | disclosed |