SCHEMBL22805331

SCHEMBL22805331

CCC(Oc1cc(F)c(Br)cc1C(F)(F)CC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
PPARA Q07869 10/20 0.36
PPARG P37231 10/20 0.35
PPARD Q03181 3/20 0.35
MAPT P10636 1/20 0.34
AAK1 Q2M2I8 1/20 0.33
PLAU P00749 2/20 0.32
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22805329 1.00 SMN1; SMN2 (0.38) SMN1; SMN2PTGDR2PPARAPPARGPPARD
SCHEMBL28694757 0.91 PPARG (0.34) PTGDR2PPARAPPARGPPARDAAK1
SCHEMBL22823742 0.91 PPARG (0.34) PTGDR2PPARAPPARGPPARDAAK1
SCHEMBL29368185 0.91 PPARG (0.34) PTGDR2PPARAPPARGPPARDAAK1
SCHEMBL22823750 0.88 AAK1 (0.34) MAPTAAK1
SCHEMBL29602077 0.88 AAK1 (0.34) MAPTAAK1
SCHEMBL28676309 0.87 PPARG (0.32) PPARAPPARGAAK1
SCHEMBL22823914 0.86 AAK1 (0.36) SMN1; SMN2PTGDR2PPARAPPARGPPARD
SCHEMBL22820787 0.86 AAK1 (0.36) SMN1; SMN2PTGDR2PPARAPPARGPPARD
SCHEMBL29365429 0.86 AAK1 (0.36) SMN1; SMN2PTGDR2PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415771-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-09-16 US disclosed
EP-3986852-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-10-16 EP disclosed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed
CN-114008012-A Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2022-02-01 CN disclosed
WO-2020254559-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2020-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 SMN1; SMN2 3/4885PTGDR2 2994/4885PPARA 3710/4885
US-12415771-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, SMN1; SMN2 SMN1; SMN2 3/4885PTGDR2 2994/4885PPARA 3710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.