SCHEMBL29368185

SCHEMBL29368185

CCC(F)(F)c1cc(Br)c(F)cc1O[C@@H](CF)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.34
PPARA Q07869 6/20 0.33
AAK1 Q2M2I8 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.30
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22823742 1.00 PPARG (0.34) PPARGPPARAAAK1PTGDR2PPARD
SCHEMBL28694757 1.00 PPARG (0.34) PPARGPPARAAAK1PTGDR2PPARD
SCHEMBL22805329 0.91 SMN1; SMN2 (0.38) PPARGPPARAAAK1PTGDR2PPARD
SCHEMBL22805331 0.91 SMN1; SMN2 (0.38) PPARGPPARAAAK1PTGDR2PPARD
SCHEMBL28697512 0.90 PPARG (0.37) PPARGPPARAPTGDR2PPARD
SCHEMBL28697514 0.90 PPARG (0.37) PPARGPPARAPTGDR2PPARD
SCHEMBL28676309 0.89 PPARG (0.32) PPARGPPARAAAK1
SCHEMBL29367638 0.88 AAK1 (0.36) PPARGPPARAAAK1PTGDR2
SCHEMBL22823754 0.88 AAK1 (0.36) PPARGPPARAAAK1PTGDR2
SCHEMBL28671829 0.88 AAK1 (0.36) PPARGPPARAAAK1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP claimed
CN-114008012-B Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2025-02-25 CN claimed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO claimed
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2022-12-08 US claimed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP claimed
CN-114008012-A Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2022-02-01 CN claimed
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP disclosed
CN-114008012-B Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2025-02-25 CN disclosed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO disclosed
EP-3986852-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2022-04-27 EP disclosed
CN-114008012-A Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388938-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS RYR1, CACNB1, SMN1; SMN2 PPARG 3395/4885PPARA 3710/4885AAK1 1187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.