Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828303 | 0.89 | CCR1 (0.37) | CCR1CCR8IDO1HCAR2IGF1R | |
| SCHEMBL31613257 | 0.76 | CCR1 (0.41) | CCR1CCR8IDO1HCAR2NPC1 | |
| SCHEMBL10715826 | 0.76 | CYP1A2 (0.51) | CCR1CCR8IDO1HCAR2IGF1R | |
| SCHEMBL14227400 | 0.74 | CYP1A2 (0.52) | CCR1CCR8IDO1IGF1RNPC1 | |
| SCHEMBL325226 | 0.73 | LMNA (0.46) | CCR1CCR8HSP90AA1L3MBTL1KMT2A | |
| SCHEMBL1577423 | 0.71 | CCR1 (0.49) | CCR1CCR8IDO1IGF1RNPC1 | |
| SCHEMBL19017897 | 0.71 | CCR1 (0.49) | CCR1CCR8IDO1HCAR2NPC1 | |
| SCHEMBL25082354 | 0.70 | CCR1 (0.47) | CCR1CCR8IDO1HCAR2NPC1 | |
| SCHEMBL26740996 | 0.69 | CCR1 (0.42) | CCR1CCR8IDO1CYP1A2ACHE | |
| SCHEMBL15976490 | 0.68 | KDM4E (0.49) | CCR1CCR8NPC1HSP90AA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220362245-A1 | COMPOUNDS FOR INHIBITING FGFR4 | TERNS PHARMACEUTICALS, INC. (US) | 2022-11-17 | — | — | US | disclosed |
| EP-3986405-A1 | COMPOUNDS FOR INHIBITING FGFR4 | Terns Pharmaceuticals, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-114144176-A | Compounds for inhibiting FGFR4 | 拓臻制药公司 | 2022-03-04 | — | — | CN | disclosed |
| WO-2020257527-A1 | COMPOUNDS FOR INHIBITING FGFR4 | Terns, Inc. (US) | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362245-A1 | COMPOUNDS FOR INHIBITING FGFR4 | FGFR4, FGFR1, FGFR3 | CCR1 4713/4885CCR8 4329/4885IDO1 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.