⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007360 | 0.75 | — | — | |
| SCHEMBL28844545 | 0.74 | — | — | |
| SCHEMBL28898156 | 0.74 | — | — | |
| SCHEMBL21628043 | 0.73 | TYR (0.46) | — | |
| SCHEMBL27764199 | 0.71 | — | — | |
| SCHEMBL21459690 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL21316492 | 0.70 | — | — | |
| SCHEMBL2273988 | 0.70 | — | — | |
| SCHEMBL310073 | 0.70 | — | — | |
| SCHEMBL7993653 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194895-A1 | PYRROL DERIVATIVES AS INHIBITORS OF APOLIPOPROTEIN L-1 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10870640-B2 | Prodigiosin analogs and methods of use | INSTITUTE FOR CANCER RESEARCH (US) | 2020-12-22 | — | — | US | disclosed |
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |