SCHEMBL22807693

SCHEMBL22807693

CC(O)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](N)CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRL1 P41146 5/20 0.46
▸ KEAP1 Q14145 2/20 0.44
▸ IL23R Q5VWK5 6/20 0.43
▸ CXCR4 P61073 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22807629 1.00 OPRL1 (0.46) OPRL1KEAP1IL23RCXCR4
SCHEMBL22807630 0.99 OPRL1 (0.46) OPRL1KEAP1IL23RCXCR4
SCHEMBL30005436 0.95 IL23R (0.45) OPRL1KEAP1IL23RCXCR4
SCHEMBL29940601 0.92 IL23R (0.46) IL23RCXCR4
SCHEMBL31737509 0.91 IL23R (0.45) OPRL1KEAP1IL23RCXCR4
SCHEMBL31737829 0.91 CXCR4 (0.44) OPRL1IL23RCXCR4
SCHEMBL29524854 0.90 IL23R (0.41) OPRL1IL23RCXCR4
SCHEMBL30596889 0.90 IL23R (0.41) OPRL1IL23RCXCR4
SCHEMBL23018562 0.90 OPRL1 (0.45) OPRL1KEAP1IL23R
SCHEMBL29540080 0.89 NPY4R (0.43) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3459546-B1 MULTI-ARM POLYMERIC TARGETING ANTI-CANCER CONJUGATE BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) 2022-01-19 — — EP disclosed
US-10869863-B2 Multi-arm polymeric targeting anti-cancer conjugate BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2020-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10869863-B2 Multi-arm polymeric targeting anti-cancer conjugate TOP2A, TOP1, ABCG2 OPRL1 3086/4885KEAP1 3561/4885IL23R 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback