SCHEMBL29940601

SCHEMBL29940601

C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](N)CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 13/20 0.46
▸ CXCR4 P61073 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30005436 0.97 IL23R (0.45) IL23RCXCR4
SCHEMBL31236827 0.96 IL23R (0.42) IL23RCXCR4
SCHEMBL30782822 0.94 IL23R (0.45) IL23RCXCR4
SCHEMBL30577893 0.93 IL23R (0.47) IL23R
SCHEMBL22807693 0.92 OPRL1 (0.46) IL23RCXCR4
SCHEMBL22807629 0.92 OPRL1 (0.46) IL23RCXCR4
SCHEMBL22807630 0.92 OPRL1 (0.46) IL23RCXCR4
SCHEMBL31737829 0.91 CXCR4 (0.44) IL23RCXCR4
SCHEMBL29374718 0.89 TFPI (0.44) IL23RCXCR4
SCHEMBL31737509 0.89 IL23R (0.45) IL23RCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222121-A1 MULTIVALENT SMAC/DIABLO PROTEIN PEPTIDOMIMETIC COVALENTLY LINKED TO A TUMOR-HOMING PEPTIDE FOR TREATING CANCERS BIOXEL INC. (US) 2025-07-10 — — US claimed
US-20250213706-A1 MULTIFUNCTIONAL PROTEOLYSIS-TARGETING CHIMERA CONJUGATES BIOXEL INC. (US) 2025-07-03 — — US claimed
CN-117695408-A Drug delivery nano-carrier and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-03-15 — — CN claimed
US-20250222121-A1 MULTIVALENT SMAC/DIABLO PROTEIN PEPTIDOMIMETIC COVALENTLY LINKED TO A TUMOR-HOMING PEPTIDE FOR TREATING CANCERS BIOXEL INC. (US) 2025-07-10 — — US disclosed
US-20250213706-A1 MULTIFUNCTIONAL PROTEOLYSIS-TARGETING CHIMERA CONJUGATES BIOXEL INC. (US) 2025-07-03 — — US disclosed
US-20240335548-A1 MACROMOLECULES STARPHARMA PTY LTD (AU) 2024-10-10 — — US disclosed
CN-117695408-A Drug delivery nano-carrier and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-03-15 — — CN disclosed
US-20220362381-A1 REMOTELY TRIGGERED THERAPY BAMBU VAULT LLC (US) 2022-11-17 — — US disclosed
CN-110124051-B Macromolecules 星法马私人有限公司 2022-10-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213706-A1 MULTIFUNCTIONAL PROTEOLYSIS-TARGETING CHIMERA CONJUGATES PSMA6, PSMA1, CUL2 IL23R 1958/4885CXCR4 2836/4885
US-20220362381-A1 REMOTELY TRIGGERED THERAPY CD47, HSP90AA1, HSF1 IL23R 1657/4885CXCR4 840/4885
US-20250222121-A1 MULTIVALENT SMAC/DIABLO PROTEIN PEPTIDOMIMETIC COVALENTLY LINKED TO A TUMOR-HOMING PEPTIDE FOR TREATING CANCERS BIRC2, BIRC3, BIRC7 IL23R 1587/4885CXCR4 206/4885
US-20240335548-A1 MACROMOLECULES BRDT, CD44, EPCAM IL23R 1587/4885CXCR4 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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