SCHEMBL22807694

SCHEMBL22807694

CCC(C)C(NC(=O)C(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(N)Cc1ccc(O)cc1)C(C)O)C(C)C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 1/20 0.62
▸ NPY2R P49146 1/20 0.62
▸ NPY4R P50391 1/20 0.62
▸ NPY5R Q15761 1/20 0.62
▸ AGTR1 P30556 2/20 0.58
▸ AGTR2 P50052 2/20 0.58
▸ GLP1R P43220 13/20 0.58
▸ MC4R P32245 2/20 0.57
▸ MC5R P33032 2/20 0.57
▸ MC3R P41968 2/20 0.57
▸ MC1R Q01726 2/20 0.57
▸ CXCR4 P61073 1/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ MUS81 Q96NY9 1/20 0.56
▸ PRLHR P49683 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496930 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RAGTR1
SCHEMBL22872738 0.97 NPY1R (0.61) NPY1RNPY2RNPY4RNPY5RAGTR1
SCHEMBL31038378 0.92 NMBR (0.63) GLP1R
SCHEMBL25460022 0.90 NMBR (0.63) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL30891928 0.90 NMBR (0.63) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL14930600 0.87 NMBR (0.58) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL25845686 0.87 NMBR (0.58) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL14930601 0.87 NMBR (0.58) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL25845917 0.86 NMBR (0.66) NPY1RNPY2RNPY4RNPY5RGLP1R
SCHEMBL25845909 0.86 NMBR (0.66) NPY1RNPY2RNPY4RNPY5RGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191843-B2 Multi-arm targeting anti-cancer conjugate BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2021-12-07 — — US disclosed
US-20210008218-A1 MULTI-ARM TARGETING ANTI-CANCER CONJUGATE BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2021-01-14 — — US disclosed
US-10869863-B2 Multi-arm polymeric targeting anti-cancer conjugate BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2020-12-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210008218-A1 MULTI-ARM TARGETING ANTI-CANCER CONJUGATE DCLRE1A, RRP12, LARP1 NPY1R 992/4885NPY2R 1855/4885NPY4R 2182/4885
US-11191843-B2 Multi-arm targeting anti-cancer conjugate LCP1, RRP12, PHLPP1 NPY1R 755/4885NPY2R 1144/4885NPY4R 1638/4885
US-10869863-B2 Multi-arm polymeric targeting anti-cancer conjugate TOP2A, TOP1, ABCG2 NPY1R 4604/4885NPY2R 4531/4885NPY4R 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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