Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.58 |
| ▸ | GRPR | P30550 | 2/20 | 0.58 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRLHR | P49683 | 1/20 | 0.51 |
| ▸ | GLP1R | P43220 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930601 | 1.00 | NMBR (0.58) | NMBRGRPRIL23RKISS1RNPY1R | |
| SCHEMBL14930600 | 1.00 | NMBR (0.58) | NMBRGRPRIL23RKISS1RNPY1R | |
| SCHEMBL25845909 | 0.94 | NMBR (0.66) | NMBRGRPRIL23RKISS1RNPY1R | |
| SCHEMBL25845917 | 0.94 | NMBR (0.66) | NMBRGRPRIL23RKISS1RNPY1R | |
| SCHEMBL22872738 | 0.91 | NPY1R (0.61) | NMBRGRPRNPY1RNPY2RNPY4R | |
| SCHEMBL25845603 | 0.90 | NTSR1 (0.54) | NPY2RNPY4RNPY5RF2 | |
| SCHEMBL25846293 | 0.90 | NTSR1 (0.54) | NPY2RNPY4RNPY5RF2 | |
| SCHEMBL31038378 | 0.88 | NMBR (0.63) | NMBRGRPRCCKBRF2GLP1R | |
| SCHEMBL22807694 | 0.87 | NPY1R (0.62) | NPY1RNPY2RNPY4RNPY5RPRLHR | |
| SCHEMBL29496930 | 0.87 | NPY1R (0.62) | NPY1RNPY2RNPY4RNPY5RPRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708393-B2 | Targeted non-invasive imaging probes of EGFR expressing cells | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708393-B2 | Targeted non-invasive imaging probes of EGFR expressing cells | EGFR, ERBB2, ERBB3 | NMBR 108/4885GRPR 70/4885IL23R 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.