SCHEMBL22808690

SCHEMBL22808690

CC1(C)c2ccccc2-c2ccc(N(c3ccccc3)c3ccc4c(ccc5c6ccc(C=C7C(=O)c8cc9ccccc9cc8C7=O)cc6ccc45)c3)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.35
KMT2A Q03164 6/20 0.35
ALDH1A1 P00352 5/20 0.35
L3MBTL1 Q9Y468 5/20 0.35
MEN1 O00255 4/20 0.35
PKM P14618 3/20 0.35
HPGD P15428 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
POLB P06746 2/20 0.35
THRB P10828 2/20 0.35
MAPK1 P28482 2/20 0.35
MDM2 Q00987 2/20 0.35
GAA P10253 2/20 0.35
TNNI3 P19429 1/20 0.35
TNNT2 P45379 1/20 0.35
TNNC1 P63316 1/20 0.35
KDM4E B2RXH2 1/20 0.34
LCK P06239 2/20 0.33
USP2 O75604 1/20 0.32
ALPL P05186 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12761750 0.93 MAPT (0.39) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL10134209 0.89 MAPT (0.40) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL12761723 0.89 LCK (0.41) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL18267270 0.89 MAPT (0.40) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL18267268 0.89 MAPT (0.38) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL18267281 0.87 MAPT (0.39) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL12761757 0.87 MAPT (0.34) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL18267271 0.87 MAPT (0.38) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL12761754 0.85 MAPT (0.34) MAPTKMT2AALDH1A1L3MBTL1MEN1
SCHEMBL15118345 0.84 MAPT (0.33) MAPTKMT2AALDH1A1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus POU2F1, PPOX, POU2F2 MAPT 1411/4885KMT2A 2954/4885ALDH1A1 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.