Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.69 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280452 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL14315246 | 0.85 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL15714003 | 0.81 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL21816582 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL17208127 | 0.79 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL7485289 | 0.74 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL5140758 | 0.71 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL3814682 | 0.70 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL7920290 | 0.68 | PARP15 (0.50) | — | |
| SCHEMBL7490724 | 0.68 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609877-B1 | PROCESS FOR THE SYNTHESIS OF FIROCOXIB | COSMA S P A (IT) | 2020-12-23 | — | — | EP | disclosed |