SCHEMBL2280920

SCHEMBL2280920

C=C(CC(N)=O)C(=C)C(=C)C(N)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278022 0.97 TDP1 (0.33) TDP1
SCHEMBL370642 0.80
SCHEMBL5695866 0.80 ALOX15 (0.41) TDP1ALOX15HSD17B10
SCHEMBL8212991 0.76 TDP1 (0.53) TDP1ALDH1A1LMNACYP1A2CYP3A4
SCHEMBL29012721 0.75 TDP1 (0.32) TDP1
SCHEMBL251231 0.75 TDP1 (0.32) TDP1
SCHEMBL7148592 0.75
Acetone SCHEMBL9144461 0.74 TDP1 (0.48) TDP1KDM4EGMNNUSP2ALDH1A1
SCHEMBL277731 0.73 MEN1 (0.32) TDP1TP53CYP1A2CYP3A4CYP2C19
SCHEMBL8917916 0.73 MEN1 (0.32) TDP1TP53CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3012302-B1 Release liner for pressure sensitive adhesives 3M INNOVATIVE PROPERTIES CO (US) 2020-09-30 EP claimed
EP-0904198-B1 Three-layer Polyamide Film Structure PLIANT CORP (US) 2004-11-17 EP claimed
CN-109715756-B Chlorine neutralizer, throw-in type chlorine neutralizer using the same, chlorine neutralizer and chlorine neutralizing method 国立大学法人三重大学 2022-10-14 CN disclosed
CN-107488264-B Phase inversion resin emulsion 施乐公司 2022-05-27 CN disclosed
WO-2018191466-A1 METHOD OF CLEANING A POLYAMIDE REACTOR BASF SE (DE) 2018-10-18 WO disclosed
EP-3131945-A1 METHOD OF PRODUCING A POLYAMIDE BASF SE (DE) 2017-02-22 EP disclosed
US-20170029566-A1 Method of Producing a Polyamide BASF SE (DE) 2017-02-02 US disclosed
WO-2015160626-A1 METHOD OF PRODUCING A POLYAMIDE BASF SE (DE) 2015-10-22 WO disclosed
US-8501898-B2 Method of forming a polyamide BASF SE (DE) 2013-08-06 US disclosed
US-20110196093-A1 METHOD OF FORMING A POLYAMIDE BASF SE (DE) 2011-08-11 US disclosed