Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424932 | 0.79 | TPMT (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL22809488 | 0.78 | KDM4E (0.39) | RAB9AKDM4ELMNAL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1424794 | 0.77 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1HTT | |
| SCHEMBL1425333 | 0.76 | KDM4E (0.46) | RAB9AKDM4ESMN1; SMN2NPC1VCP | |
| SCHEMBL1425060 | 0.75 | TPMT (0.48) | RAB9AKDM4ESMN1; SMN2NPC1PIK3CA | |
| SCHEMBL2716542 | 0.75 | ADORA3 (0.51) | RAB9ANPC1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL1425383 | 0.74 | KDM4E (0.45) | RAB9AKDM4ESMN1; SMN2NPC1VCP | |
| SCHEMBL28174158 | 0.74 | TPMT (0.42) | RAB9AKDM4ESMN1; SMN2NPC1VCP | |
| Hydrochloric Acid SCHEMBL1425309 | 0.74 | TPMT (0.47) | RAB9AKDM4ESMN1; SMN2NPC1PIK3CA | |
| SCHEMBL19151041 | 0.73 | NPSR1 (0.54) | RAB9AKDM4ELMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |