Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713671 | 0.94 | ADORA1 (0.51) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL30450912 | 0.81 | ADORA1 (0.47) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL4550822 | 0.81 | ADORA1 (0.47) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL18266209 | 0.80 | MAPT (0.39) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL2713731 | 0.80 | HSD17B10 (0.49) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL18266606 | 0.79 | MAPT (0.38) | ADORA1ADORA2AADORA3RAB9ANPSR1 | |
| SCHEMBL2713871 | 0.77 | CYP1A2 (0.58) | ADORA1ADORA3RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1178837 | 0.76 | MCHR1 (0.45) | KDM4E | |
| SCHEMBL22186405 | 0.75 | KDM4E (0.58) | ADORA1ADORA2AADORA3RAB9ALMNA | |
| SCHEMBL18266404 | 0.75 | ADORA1 (0.47) | ADORA1ADORA2AADORA3RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3487839-B1 | AMIDE DERIVATIVES AS NAV1.7 AND NAV1.8 BLOCKERS | RAQUALIA PHARMA INC (JP) | 2020-12-23 | — | — | EP | disclosed |